Contenuto dell'articolo principale
Abstract
Scopo. Studiare la prevalenza e le caratteristiche del dolore cronico nei pazienti dimessi dalla terapia intensiva ed esaminare l'associazione tra dolore e disturbi psicologici.
Metodi. Lo studio è stato condotto in una terapia intensiva (TI) italiana. Sei mesi dopo la dimissione dalla TI, i pazienti sono stati richiamati per un’intervista per valutare il dolore cronico (DC), l'intensità del dolore, la posizione del dolore e l'interferenza del dolore con le attività di vita quotidiana. Durante l’intervista è stata somministrata una batteria di test psicometrici per valutare ansia, depressione, insonnia, fatigue e disturbo da stress post-traumatico (PTSD).
Risultati. Un totale di 143 pazienti sono stati intervistati e 34 pazienti (23.8%) hanno riferito dolore. Il 70.6% degli intervistati che soffrivano di DC erano donne (p <.001). Le aree di dolore più comuni erano la spalla (16.1%), arti inferiori (11.9%) e l’area lombare (11.2%). Il maggior numero di pazienti in DC (n= 14) ha avuto dolore in 4 o più regioni anatomiche. La prevalenza di dolore cronico, ansia, depressione, insonnia, fatigue e PTSD è stata rispettivamente del 23.8%, 9.1%, 13.3%, 4.2%, 5.6% e 2.1%. L'analisi multivariata ha indicato associazioni significative tra dolore cronico e ansia (p = .003), depressione (p = .015) e insonnia (p = .027). C'è stato un grande uso di analgesici e farmaci antinfiammatori non steroidei (FANS) per il trattamento del dolore in 19 pazienti (55.9%).
Discussione. Il DC sembra associato ad alcuni disturbi psicologici osservati 6 mesi dopo una degenza. In futuro, sono necessari studi che indagano sugli interventi per prevenire il dolore cronico post-terapia intensiva.
Parole chiave. Dolore cronico, terapia intensiva, valutazione dei risultati.
Dettagli dell'articolo
Riferimenti
- Andrykowski, M.A., Cordova, M.J., Studts, J.L., Miller, T.W. (1998). Posttraumatic stress disorder after treatment for breast cancer: prevalence of diagnosis and use of the PTSD Checklist - Civilian Version (PCL-C) as a screening instrument. J Consult Clin Psychol, 66:586–90.
- Annunziata, M.A., Muzzatti, B., Mella, S., Narciso, D., Giacalone, A., Fratino, L., Tirelli, U. (2010). The revised piper fatigue scale (PFS-R) for Italian cancer patients: a validation study. Tumori, 96(2):276-81.
- Badcock, L.J., Lewis, M., Hay, E.M., McCarney, R., Croft, P.R. (2002). Chronic shoulder pain in the community: a syndrome of disability or distress? Ann Rheum Dis, 17:128–131.
- Barr, J., Fraser, G.L., Puntillo, K., Ely, E.W., Gelinas, C., Dasta, J.F., et al. (2013). Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Critical Care Medicine, 41(1):263–306.
- Battle, C.E., Lovett, S., & Hutchings, H. (2013). Chronic pain in survivors of critical illness: A retrospective analysis of incidence and risk factors. Critical Care, 17(3), R101.
- Bjelland, I., Dahl, A.A., Haug, T.T., Neckelmann, D. (2002). The validity of the Hospital Anxiety and Depression Scale. J Psychosom Res, 52:69–77.
- Boyle, M., Murgo, M., Adamson, H., Gill, J., Elliott, D., Crawford, M. (2004). The effect of chronic pain on health related quality of life amongst intensive care survivors. Australian Critical Care, 17(3):104–106.
- Castronovo, V., Galbiati, A., Marelli, S., Brombin, C., Cugnata, F., Giarolli, L., Anelli, M.M., Rinaldi, F., Ferini-Strambi, L. (2016). Validation study of the Italian version of the Insomnia Severity Index (ISI). Neurol Sci, 37(9):1517-24.
- Cleeland, C.S., Ryan, K.M. (1994). Pain assessment: Global use of the Brief pain Inventory. Annals of the Academy of Medicine, 23(2):129-38.
- Cuthbertson, B.H., Roughton, S., Jenkinson, D., MacLennan, G., Vale, L. (2010). Quality of life in the five years after intensive care: a cohort study. Crit Care, 14(1):R6.
- Damico, V., Cazzaniga, F., Murano, L., Ciceri, R., Nattino, G., Dal Molin, A. (2018). Impact of a clinical therapeutic intervention on pain assessment, management, and nursing practices in an intensive care unit: a before-and-after study. Pain Management Nursing, 19(3):256-266.
- Damico, V., Macchi, G., Murano, L., Forastieri Molinari, A. (2020). Incidence of pain at rest and during nursing procedures in ICU patients: a longitudinal observational study. Annali Igiene, 32(4):407-418.
- Damico, V., Murano, L., Cazzaniga, F., Dal Molin, A. (2018). Pain prevalence, severity, assessment and management in hospitalized adult patients: a results of a multicenter cross sectional study. Ann Ist Super Sanità, 54(3):194-200.
- Damico, V., Murano, L., Manzoni, L., Riggio, M., Dal Molin, A. (2020). The effects of a clinical therapeutic intervention in pain assessment and management in surgical ICU patients: a before-and-after intervention study on pain intensity and use of analgesia. Prof Inferm, 73(2):106-115.
- Demoro, G., Damico, V., Murano, L., Bolgeo, T., D'Alessandro, A., Dal Molin, A. (2020). Long-term consequences in survivors of critical illness. Analysis of incidence and risk factors. Ann Ist Super Sanita, 56(1):59-65.
- Devine, H., Quasim, T., McPeake, J., Shaw, M., Mccallum, L., Mactavish, P. (2019). Chronic pain in intensive care unit survivors: incidence, characteristics and side-effects up to one-year post-discharge. J Rehabil Med, 18;51(6):451-455.
- Dowdy, D.W., Eid, M.P., Sedrakyan, A., Mendez-Tellez, P.A., Pronovost, P.J., Herridge, M.S., Needham, D.M. (2005). Quality of life in adult survivors of critical illness: a systematic review. Intensive Care Med, 17:611–620.
- Duggan, M.C., Wang, L., Wilson, J.E., Dittus, R.S., Ely, E.W., Jackson J.C. (2016). The relationship between executive dysfunction, depression, and mental health-related quality of life in survivors of critical illness: Results from the BRAIN-ICU investigation. Journal of Critical Care, 37:72–79.
- Finan, P.H., Goodin, B.R., Smith, M.T. (2013). The association of sleep and pain: an update and a path forward. J Pain, 14(12):1539-52.
- Hatch, R., Young, D., Barber, V., Griffiths, J., Harrison, D.A., Watkinson, P. (2018). Anxiety, Depression and Post Traumatic Stress Disorder after critical illness: a UK-wide prospective cohort study. Critical Care, 23;22(1):310.
- Jacodic, H.K., Jacodic, K., Podbregar, M. (2006). Long term outcome and quality of life of patients treated in a surgical intensive care: a comparison between sepsis and trauma. Critical Care, 17:R134.
- Jenewein, J., Moergeli, H., Wittmann, L., Büchi, S., Kraemer, B., Schnyder, U. (2009). Development of chronic pain following severe accidental injury. Results of a 3-year follow-up study. J Psychosom. Res, 66:119–126.
- Katz, J., Rosenbloom, B.N., Fashler, S. (2015). Chronic pain, psychopathology, and DSM-5 somatic symptom disorder. Can J Psychiatry, 60:160–167.
- Kemp, H.I., Laycock, H., Costello, A., Brett, S.J. (2019). Chronic pain in critical care survivors: a narrative review. Br J Anaesth, 123(2): e372–e384.
- Kong, K.H., Woon, V.C., Yang, S.Y. (2004). Prevalence of chronic pain and its impact on health-related quality of life in stroke survivors. Archives of Physical Medicine and Rehabilitation, 85(1):35–40.
- Labriola, J.E., Lee, T.Q., Debski, R.E., McMahon, P.J. (2005). Stability and instability of the glenohumeral joint: the role of shoulder muscles. J Shoulder Elbow Surg, 17:32–38.
- Langerud, A.K., Rustøen, T., Brunborg, C., Kongsgaard, U., Stubhaug, A. (2018). Prevalence, Location, and Characteristics of Chronic Pain in Intensive Care Survivors. Pain Manag Nurs, 19(4):366-376.
- Lipman, A.G. (2005). Pain as a human right: The 2004 global day against pain. J Pain Palliat Care Pharmacother, 19:85-100.
- Melotti, R.M., Samolsky-Dekel, B.G, Ricchi, E., Chiari, P., Di Giacinto, I., Carosi, F., Di Nino, G.F. (2005). Pain prevalence and predictors among inpatients in a major Italian hospital. A baseline survey towards a pain free hospital. European Journal of Pain, 9:485-95.
- Nasreddine, Z.S., Phillips, N.A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Cummings, J.L., Chertkow, H. (2005). The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc, 53(4):695–9.
- Nicholas, M., Vlaeyen, J.W.S., Rief, W., Barke, A., Aziz, Q., Benoliel, R., et al. (2019). The IASP classification of chronic pain for ICD-11: chronic primary pain. Pain, 160(1):28-37.
- Pinto, T.C.C., Machado, L., Bulgacov, T.M., Rodrigues-Júnior, A.L., Costa, M.L.G., Ximenes, R.C.C., Sougey, E.B. (2019). "Is the Montreal Cognitive Assessment (MoCA) screening superior to the Mini-Mental State Examination (MMSE) in the detection of mild cognitive impairment (MCI) and Alzheimer's Disease (AD) in the elderly?". International Psychogeriatrics, 31(4): 491–504.
- Sheng, J., Liu, S., Wang, Y., Cui, R., Zhang, X. (2017). Neural Plast. The Link between Depression and Chronic Pain: Neural Mechanisms in the Brain, 9724371.
- Smith, B.H., Fors, E.A., Korwisi, B., Barke, A., Cameron, P., Colvin, L., Richardson, C., et al. (2019). The IASP classification of chronic pain for ICD-11: applicability in primary care. Pain, 160(1):83-87.
- Snaith, R.P., & Zigmond, A.S. (1994). The Hospital Anxiey and Depression Scale with the Irritability-depression-anxiety Scale and the Leeds Situational Anxiety Scale: manual version 1994.
- Stamenkovic, D.M., Laycock, H., Karanikolas, M., Ladjevic, N.G., Neskovic, V., Bantel, C. (2019). Chronic Pain and Chronic Opioid Use After Intensive Care Discharge - Is It Time to Change Practice? Front Pharmacol, 22:10-23.
- Tan, G., Jensen, M.P., Thornby, J.I., Shanti, B.F. (2004). Validation of the Brief pain Inventory for chronic nonmalignant pain. Journal of Pain, 5(2):133-7.
Riferimenti
Andrykowski, M.A., Cordova, M.J., Studts, J.L., Miller, T.W. (1998). Posttraumatic stress disorder after treatment for breast cancer: prevalence of diagnosis and use of the PTSD Checklist - Civilian Version (PCL-C) as a screening instrument. J Consult Clin Psychol, 66:586–90.
Annunziata, M.A., Muzzatti, B., Mella, S., Narciso, D., Giacalone, A., Fratino, L., Tirelli, U. (2010). The revised piper fatigue scale (PFS-R) for Italian cancer patients: a validation study. Tumori, 96(2):276-81.
Badcock, L.J., Lewis, M., Hay, E.M., McCarney, R., Croft, P.R. (2002). Chronic shoulder pain in the community: a syndrome of disability or distress? Ann Rheum Dis, 17:128–131.
Barr, J., Fraser, G.L., Puntillo, K., Ely, E.W., Gelinas, C., Dasta, J.F., et al. (2013). Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Critical Care Medicine, 41(1):263–306.
Battle, C.E., Lovett, S., & Hutchings, H. (2013). Chronic pain in survivors of critical illness: A retrospective analysis of incidence and risk factors. Critical Care, 17(3), R101.
Bjelland, I., Dahl, A.A., Haug, T.T., Neckelmann, D. (2002). The validity of the Hospital Anxiety and Depression Scale. J Psychosom Res, 52:69–77.
Boyle, M., Murgo, M., Adamson, H., Gill, J., Elliott, D., Crawford, M. (2004). The effect of chronic pain on health related quality of life amongst intensive care survivors. Australian Critical Care, 17(3):104–106.
Castronovo, V., Galbiati, A., Marelli, S., Brombin, C., Cugnata, F., Giarolli, L., Anelli, M.M., Rinaldi, F., Ferini-Strambi, L. (2016). Validation study of the Italian version of the Insomnia Severity Index (ISI). Neurol Sci, 37(9):1517-24.
Cleeland, C.S., Ryan, K.M. (1994). Pain assessment: Global use of the Brief pain Inventory. Annals of the Academy of Medicine, 23(2):129-38.
Cuthbertson, B.H., Roughton, S., Jenkinson, D., MacLennan, G., Vale, L. (2010). Quality of life in the five years after intensive care: a cohort study. Crit Care, 14(1):R6.
Damico, V., Cazzaniga, F., Murano, L., Ciceri, R., Nattino, G., Dal Molin, A. (2018). Impact of a clinical therapeutic intervention on pain assessment, management, and nursing practices in an intensive care unit: a before-and-after study. Pain Management Nursing, 19(3):256-266.
Damico, V., Macchi, G., Murano, L., Forastieri Molinari, A. (2020). Incidence of pain at rest and during nursing procedures in ICU patients: a longitudinal observational study. Annali Igiene, 32(4):407-418.
Damico, V., Murano, L., Cazzaniga, F., Dal Molin, A. (2018). Pain prevalence, severity, assessment and management in hospitalized adult patients: a results of a multicenter cross sectional study. Ann Ist Super Sanità, 54(3):194-200.
Damico, V., Murano, L., Manzoni, L., Riggio, M., Dal Molin, A. (2020). The effects of a clinical therapeutic intervention in pain assessment and management in surgical ICU patients: a before-and-after intervention study on pain intensity and use of analgesia. Prof Inferm, 73(2):106-115.
Demoro, G., Damico, V., Murano, L., Bolgeo, T., D'Alessandro, A., Dal Molin, A. (2020). Long-term consequences in survivors of critical illness. Analysis of incidence and risk factors. Ann Ist Super Sanita, 56(1):59-65.
Devine, H., Quasim, T., McPeake, J., Shaw, M., Mccallum, L., Mactavish, P. (2019). Chronic pain in intensive care unit survivors: incidence, characteristics and side-effects up to one-year post-discharge. J Rehabil Med, 18;51(6):451-455.
Dowdy, D.W., Eid, M.P., Sedrakyan, A., Mendez-Tellez, P.A., Pronovost, P.J., Herridge, M.S., Needham, D.M. (2005). Quality of life in adult survivors of critical illness: a systematic review. Intensive Care Med, 17:611–620.
Duggan, M.C., Wang, L., Wilson, J.E., Dittus, R.S., Ely, E.W., Jackson J.C. (2016). The relationship between executive dysfunction, depression, and mental health-related quality of life in survivors of critical illness: Results from the BRAIN-ICU investigation. Journal of Critical Care, 37:72–79.
Finan, P.H., Goodin, B.R., Smith, M.T. (2013). The association of sleep and pain: an update and a path forward. J Pain, 14(12):1539-52.
Hatch, R., Young, D., Barber, V., Griffiths, J., Harrison, D.A., Watkinson, P. (2018). Anxiety, Depression and Post Traumatic Stress Disorder after critical illness: a UK-wide prospective cohort study. Critical Care, 23;22(1):310.
Jacodic, H.K., Jacodic, K., Podbregar, M. (2006). Long term outcome and quality of life of patients treated in a surgical intensive care: a comparison between sepsis and trauma. Critical Care, 17:R134.
Jenewein, J., Moergeli, H., Wittmann, L., Büchi, S., Kraemer, B., Schnyder, U. (2009). Development of chronic pain following severe accidental injury. Results of a 3-year follow-up study. J Psychosom. Res, 66:119–126.
Katz, J., Rosenbloom, B.N., Fashler, S. (2015). Chronic pain, psychopathology, and DSM-5 somatic symptom disorder. Can J Psychiatry, 60:160–167.
Kemp, H.I., Laycock, H., Costello, A., Brett, S.J. (2019). Chronic pain in critical care survivors: a narrative review. Br J Anaesth, 123(2): e372–e384.
Kong, K.H., Woon, V.C., Yang, S.Y. (2004). Prevalence of chronic pain and its impact on health-related quality of life in stroke survivors. Archives of Physical Medicine and Rehabilitation, 85(1):35–40.
Labriola, J.E., Lee, T.Q., Debski, R.E., McMahon, P.J. (2005). Stability and instability of the glenohumeral joint: the role of shoulder muscles. J Shoulder Elbow Surg, 17:32–38.
Langerud, A.K., Rustøen, T., Brunborg, C., Kongsgaard, U., Stubhaug, A. (2018). Prevalence, Location, and Characteristics of Chronic Pain in Intensive Care Survivors. Pain Manag Nurs, 19(4):366-376.
Lipman, A.G. (2005). Pain as a human right: The 2004 global day against pain. J Pain Palliat Care Pharmacother, 19:85-100.
Melotti, R.M., Samolsky-Dekel, B.G, Ricchi, E., Chiari, P., Di Giacinto, I., Carosi, F., Di Nino, G.F. (2005). Pain prevalence and predictors among inpatients in a major Italian hospital. A baseline survey towards a pain free hospital. European Journal of Pain, 9:485-95.
Nasreddine, Z.S., Phillips, N.A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Cummings, J.L., Chertkow, H. (2005). The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc, 53(4):695–9.
Nicholas, M., Vlaeyen, J.W.S., Rief, W., Barke, A., Aziz, Q., Benoliel, R., et al. (2019). The IASP classification of chronic pain for ICD-11: chronic primary pain. Pain, 160(1):28-37.
Pinto, T.C.C., Machado, L., Bulgacov, T.M., Rodrigues-Júnior, A.L., Costa, M.L.G., Ximenes, R.C.C., Sougey, E.B. (2019). "Is the Montreal Cognitive Assessment (MoCA) screening superior to the Mini-Mental State Examination (MMSE) in the detection of mild cognitive impairment (MCI) and Alzheimer's Disease (AD) in the elderly?". International Psychogeriatrics, 31(4): 491–504.
Sheng, J., Liu, S., Wang, Y., Cui, R., Zhang, X. (2017). Neural Plast. The Link between Depression and Chronic Pain: Neural Mechanisms in the Brain, 9724371.
Smith, B.H., Fors, E.A., Korwisi, B., Barke, A., Cameron, P., Colvin, L., Richardson, C., et al. (2019). The IASP classification of chronic pain for ICD-11: applicability in primary care. Pain, 160(1):83-87.
Snaith, R.P., & Zigmond, A.S. (1994). The Hospital Anxiey and Depression Scale with the Irritability-depression-anxiety Scale and the Leeds Situational Anxiety Scale: manual version 1994.
Stamenkovic, D.M., Laycock, H., Karanikolas, M., Ladjevic, N.G., Neskovic, V., Bantel, C. (2019). Chronic Pain and Chronic Opioid Use After Intensive Care Discharge - Is It Time to Change Practice? Front Pharmacol, 22:10-23.
Tan, G., Jensen, M.P., Thornby, J.I., Shanti, B.F. (2004). Validation of the Brief pain Inventory for chronic nonmalignant pain. Journal of Pain, 5(2):133-7.